Peptide pools is usually utilized for a broad selection of purposes: Antigen-certain stimulation in T-cell assays
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Having said that, peptide swimming pools could also consist of numerous small peptide sequences that stand for vital immunodominant epitopes of varied viruses.
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Strengths contain resistance to dewetting, compatibility with 100% aqueous cellular phases, choice selectivity to HALO C18 and for a longer period retention of polar compounds than typical C18 phases underneath most mobile section problems.
Peptide Swimming pools may be used to stimulate antigen-precise CD4+ and CD8+ T cells. The activated T cells can then be detected, quantified or isolated for Examination based on unveiled cytokines and upregulated activation markers.